PA-PRP – (Photoactivated Platelet Rich Plasma)
is inherently safe because the cells which heal are not taken from another human being or animal. They are you own cells taken from your own body – and used to repair your own body.
Since PRP is an autologous concentration of platelets in a small volume of plasma taken from your own blood, there are no contraindications or adverse side effects.
PRP and PA-PRP Processes are Autologous.
Growth factors also have a role in signaling mesenchymal stem cells to proliferate and differentiate inside the area to be repaired. They act like “homing signals”.
Thousands of Research Articles have been published on the safety and efficacy of the PRP Prpocedure over the past 30 years.
PRP Procedures are Approved by the USFDA.
When your PRP is PhotoActivated, You Jump Start the Natural Healing Cascade
The PA-PRP procedure is simple. Your blood is withdrawn as usual, spun in a centrifuge and the PRP is collected from the top of the Tubes, which contain an anticoagulant, and then transferred into a syringe. After this standard procedure, your doctor places the syringe into a chamber for an extra 10 minutes to PhotoActivate the PRP.
The process has not been widely shown to significantly reduce joint pain and accelerate healing. PA-PRP adds anti-inflammatory benefits of photoactivation to the PRP which is a concentrated source of platelets rich in growth and cytokines that accelerate and enhance the healing of bone and soft tissue.
For patients this means two things
- The aggravated pain of a standard PRP procedure in the affected area is significantly reduced by the photoactivation which reduces inflammation, increases the production of natural pain killers and releases beta endorphins. This means relief from pain in a couple of days – rather than in weeks or months when photoactivation is not used.
- The PA-PRP Therapy has also been found to stimulate cartilage and tissue repair and to reduce pain and inflammation to the extent of either delaying invasive surgery – or even making it unnecessary.
NOTE: PhotoActivated PRP (PAPRP) is also being used successfully in cosmetic and aesthetic procedures for facial rejuvenation – and for hair loss via injection into the scalp.
Why PhotoActivation Works
Research shows the effect of different monochromatic light intensities and frequencies in the colored spectrum on human and animal cell populations such as mesenchyme stem cells and white blood cells. Through the use of three color spectrums (red, yellow and green at particular frequencies), white blood cells are signaled to release IL-IRA and beta endorphins. Interleukin I Receptor Antagonist is a potent anti-inflammatory agent and reduces the pain associated with standard PRP injections. The duration of any pain is also significantly reduced.
In other words, the use of PhotoActivation stimulates other regenerative cells which jump starts the natural healing cascade. Inflammation mesenchymal stem cells are recruited to help the area of injury.
The PhotoActivation process adds only 10 minutes to the normal PRP procedure.
Platelets Contain Growth Factors and Release BioActive Proteins
Research Paper from the British Medical Journal on “PA-PRP Therapy for a Traumatic Knee Chondrial Lesion” (Published December 2012)
MRI taken 3 months post-photoactivated platelet-rich bial plasma injections resolution of the subchondral bone marrow oedema but no structural change in the chondral flap.
Studies indicate that platelets contain over 400 growth factor components and cytokines that are crucial in soft tissue healing and bone regeneration.
Research shows that platelets also release many bioactive proteins responsible for attracting macrophages, mesenchymal stem cells and osteoblasts that not only promote removal of degenerated and necrotic tissue, but also enhance tissue regeneration and healing.
Healing of Your MusculoSkeletal Pain is Accelerated and Pain is Reduced When your PRP is PhotoActivated (PAPRP) for:
Osteoarthritis: Knees, Neck, Lower Back, Hip, Elbow and Small Joints: Muscle Tears and Sprains: Tendon Injuries: Ligament Injuries: Spine and Shoulder Disorders: Rotator Cuff Tears; Chronic Plantar Fasciitis: Bursitis and other Painful Musculoskeletal Disorders. Normal Protocol: One Injection per Week for 3-6 Weeks The whole process of PA-PRP takes about 30 minutes.
PRP is Becoming More Popular
How PRP is PhotoActivated
- After centrifugating, the blood will fractionate, and the PRP will on top and the Red Blood Cells at bottom
- PRP is collected and placed syringe in a Light machine for 10 minutes to PhotoActivatate
- The PA-PR is now ready for injection. An ultrasound guided injection can be used if necessary to ensure the PRP is placed exactly into the injured tissue. The doctor may also inject some local anaesthetic into the region.